Biotech Engineering Calculators

Residence Time

Calculate residence time in a bioreactor

Mass Flow Rate

Calculate mass flow rate in a system

Energy Balance

Calculate energy balance in a system

Heat Exchanger

Calculate heat exchanger parameters

Mixing Time

Calculate mixing time in a vessel

Aeration Rate

Calculate aeration rate in a bioreactor

pH Adjustment

Calculate pH adjustment requirements

Dry/Wet Basis

Convert between dry and wet basis

Evaporation Rate

Calculate evaporation rate

Centrifuge Sizing

Calculate centrifuge parameters

Steam Requirement

Calculate steam requirements

Pump Power

Calculate pump power requirements

Viscosity/Reynolds

Calculate Reynolds number, flow regime, and kinematic viscosity.

Cooling Time

Calculate cooling time for a fluid

Gibbs Energy Yield

Estimate Gibbs energy consumption for biomass yield based on thermodynamics.

Maintenance Energy (m\u209g)

Calculate maintenance energy rate (m\u209g) based on temperature.

Max Gibbs Production Rate (qmaxG)

Calculate max rate of Gibbs energy production from thermodynamics.

Max Specific Growth Rate (μmax)

Calculate μmax based on thermodynamics and temperature.

Doubling Time (td)

Calculate biomass doubling time from specific growth rate.

Yield Coefficient (Ysx/Ysp)

Calculate biomass or product yield from specific rates.

Monod Kinetics (μ)

Calculate specific growth rate based on substrate concentration.

Multi-Substrate Min Kinetics (μ)

Calculate μ limited by the minimum of two substrates (Monod).

Substrate Inhibition Kinetics (μ)

Calculate μ with Monod model including substrate inhibition.

Product Inhibition Kinetics (μ)

Calculate μ with Monod model including product inhibition.

Observed Yield (Ysx)

Calculate observed biomass yield considering maintenance (ms).

pH Effect on μmax

Calculate μmax based on pH and enzyme dissociation constants.

Optimal Dilution Rate (Dopt)

Calculate Dopt for max productivity (no maintenance).

Heat Transfer Coefficient (ho)

Calculate broth-side ho for stirred tanks (coils/jacket).

Bubble Column ho

Calculate heat transfer coefficient (ho) for bubble columns.

Unit Converter

Universal Imperial/Metric Unit Converter.

Shear Rate/Stress (γ, τ)

Calculate avg shear rate/stress in stirred tanks (Newtonian/Non-Newtonian).

Energy Input (E) - Bubble/Airlift

Calculate energy input per unit mass (E) for Bubble Columns & Airlift reactors.

Stirred Tank Power/Energy (P, PG, E)

Calculate P, PG, and E for stirred tanks (Laminar/Turbulent).

Bubble Column kLa & Holdup (ε)

Calculate kLa and gas holdup (ε) for bubble columns.

Feed Rate

Calculate required feed rate for fed-batch culture.

Reactor Volume

Calculate required reactor volume based on flow and residence time.

Centrifuge Max Throughput (Φv)

Calculate max volumetric throughput for centrifuges using Stokes' law.

Plant Investment Cost

Estimate plant fixed capital based on EPC and Lang factors.

Batch Enzyme Kinetics Time (t)

Calculate time for batch enzyme reaction using integrated M-M eq.

Allosteric Enzyme Velocity (v)

Calculate reaction velocity for allosteric enzymes (Hill eq.).

Wall Heat Conduction (Q̇)

Calculate heat conduction rate through a flat wall (Fourier's Law).

Counterflow Heat Exchanger

Calculate Heat Duty (Q), LMTD, and Area (A) for counterflow exchangers.